Bactroban cream is a topical medication used to treat skin infections caused by certain bacteria. It contains the active ingredient mupirocin, which has antibacterial properties. Here's a detailed explanation of Bactroban cream, including its chemical formula, mechanism of action, indications, uses, administration, and side effects.
The chemical formula of mupirocin, the active ingredient in Bactroban cream, is C26H44O9. It is an antibiotic derived from the fermentation of Pseudomonas fluorescens.
Mechanism of Action:
Mupirocin works by inhibiting bacterial protein synthesis. It specifically binds to bacterial isoleucyl transfer-RNA synthetase, an enzyme involved in protein synthesis, thereby preventing the incorporation of isoleucine into bacterial proteins.
This inhibits the growth and replication of susceptible bacteria, particularly Staphylococcus aureus and Streptococcus pyogenes.
Indications and Uses:
Bactroban cream is primarily indicated for the treatment of skin infections caused by susceptible bacteria. It is commonly used for impetigo, a highly contagious bacterial skin infection characterized by red sores that quickly develop into honey-colored crusts.
Bactroban cream may also be used for other minor skin infections, such as folliculitis, infected eczema, and small infected cuts or wounds.
Bactroban cream is for external use only and should be applied to the affected area of the skin as directed by a healthcare professional.
Before applying the cream, the affected area should be cleansed and dried thoroughly. A small amount of Bactroban cream is then applied and gently massaged into the skin.
It is important to follow the prescribed dosage and treatment duration.
Generally, Bactroban cream is applied two to three times daily for up to 10 days, or as directed by the healthcare provider.
It is crucial to avoid contact with the eyes, nose, mouth, and other mucous membranes when using Bactroban cream.
If accidental contact occurs, the area should be rinsed with water immediately.
Bactroban cream is generally well-tolerated when used as directed. However, like any medication, it can cause side effects in some individuals.
Common side effects may include mild burning, stinging, itching, or dryness at the application site. These side effects are usually temporary and resolve on their own.
In rare cases, allergic reactions may occur, characterized by severe itching, swelling, rash, or difficulty breathing.
If any signs of an allergic reaction occur, immediate medical attention should be sought.
It is important to note that prolonged or excessive use of Bactroban cream may increase the risk of developing bacterial resistance or superinfection.
If the infection does not improve or worsens after several days of treatment, it is important to consult a healthcare professional.
It's worth noting that the information provided here is a general overview, and the specific instructions, precautions, and potential side effects of Bactroban cream may vary.
It is always recommended to consult a healthcare professional or refer to the product's prescribing information for detailed and accurate information specific to the medication and its usage.